Modafinil Side Effects, Interaction with Alcohol & Other Drugs
Eugeroics were originally invented as wakefulness-promoting agents to treat various sleep disorders. Now people found them to be a real panacea if you want to acquire additional concentration and cognitive enhancement. Modafinil, a pioneer among smart drugs, can be very helpful, but only if you strictly follow all instructions of your doctor and the guidelines for medical use.
Provigil is the certified trade name of modafinil tablets in the United States. According to American medical authorities, Provigil is a schedule IV controlled substance. This means that the commercialization and usage of this medicine is restricted, because it carries a risk of creating an addiction. What if we tell you that there is an easy way to buy modafinil without any red tape, and even cheaper than in a local pharmacy? Our online drugstore ModafinilXL offers inexpensive but efficient generic smart drugs, manufactured by the reputable and trustworthy Indian pharmacists.
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Before Taking Modafinil
You will be interested to know a little about the history of modafinil’s development and licensing, as well as how it influenced working people and students all over the world. The famous french neuroscientist and novator in healthcare and pharmaceutics, Michel Valentin Marcel Jouvet, invented this medicinal drug in cooperation with Lafon Laboratories. France approved Modafinil and allowed its prescription under the name Modiodal in 1994, and four years later the American Food and Drug Administration (FDA) gave a license to the new preparation to treat narcolepsy. Such sleeping ailments as obstructive sleep apnea/hypopnea and shift work sleep disorder, were approved by the FDA for modafinil treatment in 2003.
The US brand name of this drug is Provigil. In 2007, Cephalon Inc., the same company that produces Provigil, started marketing the derivative medicinal compound Armodafinil under the name Nuvigil. In ModafinilXL online pharmacy you can buy generic versions of these pills — Modvigil 200mg and Modalert 100mg and 200 mg. In the USA, China, Japan, Russian Federation, and some other countries, modafinil is a strictly controlled substance, but there are jurisdictions where you can buy the tablets in any pharmacy as long as you have a doctor’s prescription. The United Kingdom, South Africa, Mexico, Finland, Norway, and some others are among them.
Modafinil is a dopamine increasing agent, and due to this mechanism of action, it is used off-label by students and white-collar workers as the nootropic drug. It was shown to improve memory, learning capacities, and executive functions. Modafinil was trialed for many purposes. Transhumanists tried to use this smart drug to widen the horizons of a human’s intellect. Military medics tested modafinil as an attention, concentration, and motivation enhancer. It was supposed to elevate such characteristics as alert reaction time, active attention to details, and the ability to make correct judgments and decisions in situations where a person has a lack of sleep.
Many sportsmen used Nuvigil as a drug that improved their energy and performance. In 2004, it was prohibited by the World Anti-Doping Agency. It was reported that modafinil increased the maximum time of exercising as well as decreases the perceived exertion. Other not licensed uses of modafinil include for attention deficit hyperactivity disorder, schizophrenia, weight loss, and cognitive impairments in patients who take chemotherapy. It did not show any effects in mood stabilization, appetite, or metabolism. Though the results in cognitive enhancement were more significant, the possible negative consequences, like adverse reactions and interactions with other drugs, did not allow medical authorities to approve those indications. Wakefulness promotion remains the only legal usage of modafinil.
Common Modafinil Side Effects
In our drugstore, the Modafinil tablet costs only $0.79, which make it a very inexpensive way to improve the professional lives and studies for huge amounts of our customers. If you take a look at their reviews, you will see how our drugs change their lives. People discover the hidden energy in their bodies, stop feeling lethargic and apathetic, and think brighter and quicker. But the status of the schedule IV controlled substance is not given without a reason. We honestly inform our clients about possible side effects and precautions that should be taken in order to administer Modafinil safe and sound.
Let’s divide the side effects into two groups:
- side effects that do not pose any danger to your health;
- adverse reactions that demand immediate professional medical intervention.
Primarily, you need to know about the second group. They can be the symptoms of overdose, or negative or allergic reactions from your body. The slightest signs of skin hypersensitivity, sudden hives, turgidity of the upper airways, face, lips, eyelids, joints, extremities, etc., or troubled breathing are reasons to stop using the medication immediately and go to a hospital.
Other dangerous signs are:
- cognitive and psychiatric dysfunctions, like depression, suicidal ideas, unmotivated aggressiveness and anxiety, hallucinations, disorientation, excessive agitation, memory loss, etc.;
- cardiovascular problems, such as a higher heart rhythm or hypertension, chest pain and tightness;
- troubles with the bladder and urination — any changes in color and body of urine, pains and burns, inability to pass water;
- dangerously high temperature or chills, fatigue, tremors and shakes, etc.
These undesired reactions occur much more rarely than Provigil negative effects such as headache and sickness. The latter do not demand any strong medical measures, unless they grow into a serious problem that affects your normal life.
Less Common Side Effects
There are very rare side effects, such as fainting, long-term bleeding, bruises that stay for an unusually long time, vision and hearing impairments, black stool, etc. They are also the symptoms of an adverse and undesired reaction of your organism to the medication. It is better to consult a doctor and cease administering modafinil pills if they occur.
Less common unwanted treatment consequences that do not require medical assistance are:
- the symptoms of the common cold — coughing, sneezing, runny nose;
- pains in joints, back, legs, and arms;
- digestion problems, like cardialgia, stomach upset, diarrhea, constipation, belching, or vomiting;
- dizziness, nervousness;
- unusual sensations of the skin and mouth — dryness, pins and needles, burns, and itchiness;
- appetite loss.
Anyway, it is better to be safe than sorry, so we recommend that you report all changes in your health and general state during your time consuming modafinil to your healthcare provider.
There is such a term in medicine called the honeymoon phase of the drug. It is not a side effect, but it is important to remember it exists. The first days of administration are distinctive in the strength of action of the usual doses of the medications. This can be explained by several factors, like the placebo effect and being new to the treatment. But the main factor is the absence of tolerance. Until you have not developed any tolerance, you feel the effects of modafinil stronger.
Interaction of Modafinil and Food
Modafinil should be taken once a day, at the same hour every day. If you have apnea or narcolepsy, the pills are administered in the morning, when the reason for the sleep disorder is the working schedule, you should take the drug one hour before your shift starts. Usually, doctors prescribe 200 mg of modafinil per day, without it being bound to meals. It is better to talk to a doctor to establish your personal method and rate of administration. Never change the dose, time of intake, or discontinue the drug by yourself, as the risk of severe withdrawal is very high. Never take a double dose, even if you missed one consumption by mistake — just skip it.
The prescribed doses may be higher, up to 400 mg per day. In such cases, users report that it is better to take the tablets on a full stomach. With lower amounts of the medicine, food can delay its action. With the maximum dosages, a full stomach can make the effects smoother, and the patients testify that they feel less irritated and disturbed when they make modafinil a part of their breakfast. Also, it helps them not to miss a dose and take it always at the same time.
Modafinil and Grapefruit Interaction
If another part of your breakfast is a grapefruit or its juice, you should inform your doctor about that. This combination is not necessarily dangerous, but these citrus fruits contain the compound that influences the chemical and biological development of modafinil in the body. More specifically, it increases the action and prolongs the occurrence of the drug in the blood. Thus, grapefruits can increase the risk of adverse reactions. With proper medical assistance, correct dosages, and abidance by the rules and instructions, you can combine your medications and breakfast traditions.
Modafinil and Alcohol
As modafinil should be delivered regularly, and the adherence to the schedule of administration and dosages should be flawless, there is a great concern about this drug among people who drink alcohol several times a week. Lots of them do not want to give up their habits and way of life, and the question is — is it dangerous to use Provigil or its generics and alcohol together? We told you about the honeymoon phase of drugs, and spirits also have a phase like this. The general rule you have to remember is that nootropic drugs, which change the chemical and biological processes in the brain, usually make you a freshman in drinking. This means that the sooner you get the first shot after the modafinil pill, the less tolerance to alcohol you have.
Drinking Alcohol the Next Day After Taking Modafinil
If you have more than 15 hours between the Provigil tablet and your favorite liquor, you will not feel any difference. The half-life of the drug is a little bit more than a half of a day, thus your blood will not contain any of this medicinal product by the next evening. Remember, though, that to drink alcohol without any unwanted effects of the medication, you have to skip a daily dose, which is highly not recommended. So do it only if it is really necessary—on special occasions, for example.
Alcohol and Modafinil on the Same Day
The result of taking both alcohol and modafinil in the same day depends on how soon you start drinking. Make a gap of at least 10 hours, take a pill in the morning and in the evening you will have a usual party with friends with no embarrassing or even dangerous consequences. Many users say that they felt even better than usual, and their cognition, speech, motion functions were close to normal.
Less than 6 hours means that alcohol will just turn you off without even making you really drunk. Commonly, people do not remember what they did or said after such experiments. And it is necessary to have enough sleep after the party to avoid a terrible hangover.
Drinking Alcohol Immediately After Taking Modafinil
Our answer for this is “No!” You should never take your daily dose of nootropic medication and drink alcoholic beverages a few minutes later. Some people state that nothing bad has happened to them after doing so and they even managed to have fun. Most users, though, write in reviews and blogs that they felt sick right after the first glass of beer and could not walk, let alone drive a car. Some say that it was impossible to control their emotions and the feeling was as if they drank a dose close to fatal.
Can I Take Modafinil with Coffee?
Caffeine is a wakefulness-promoting substance, the same is modafinil, so their effects coincide. It is not extremely dangerous if you drink a cup of coffee right after or before taking a pill. Still, it is better to control the doses of caffeine you consume during the day, whether from tea, chocolates, sweet drinks, etc. Consult with your doctor and adjust your diet to your treatment with the help of a professional. It is better to wash down the tablet with plain water.
Interaction with Other Drugs
Different drugs, taken together, may change the action of each other or cause serious damage to your health. Modafinil has a list of the drug interactions that should be followed meticulously. Your doctor must know about all medicinal products you use at the moment.
Accurately name all drugs, herbs, and dietary supplements you take or took during previous month:
- other nootropics, antidepressants, antipsychotics, and so-called recreation (or simply illegal) drugs are to be avoided when you use modafinil;
- drugs that treat severe cases of hepatitis, HIV, or cancer may not perform together with Provigil, or they may mutually reduce the effectiveness of each other;
- if you are under any cardiovascular treatment, take blood pressure regulators, or had a stroke or heart attack in the past, you can take modafinil only under medical control;
- hormonal preparations for interception lose their effectiveness in the presence of modafinil in the blood. Do not use them even 30 days after the last Provigil tablet;
- if you use any antifungals, antibiotics, or direct-acting antivirals, talk to your doctor, as some of them do not perform their action when taken together with modafinil.
To make a long story short, always remember your health and do not forget that Provigil and generic drugs are serious medications that can make your life easier and brighter, but at the same time can do much harm. These pills should not be used without a doctor’s advice and assistance. If you follow this rule, our online pharmacy ModafinilXL will gladly become a provider of your new, brighter and easier life.