Although the exact method of action for Modalert is not completely known, researchers have found that the drug is very effective in crossing the blood-brain barrier. At this point, it can enter the central nervous system and work to inhibit the reuptake of dopamine. Dopamine is a neurotransmitter, commonly known as the “feel-good” transmitter.
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Daytime sleepiness and difficulty falling asleep at night are common problems that affect a large portion of our society.
In the United States alone, up to 40% of the population is affected in some way with sleep issues like narcolepsy, shift work sleep disorders, excessive daytime sleepiness and insomnia. Modalert was designed specifically as a medication to help individuals with sleep issues to improve cognitive function and to help maintain a healthy sleep cycle.
Modalert is a brand of modafinil created by Sun Pharma, the leading manufacturer in Modalert drugs. Modafinil is what is known as an eugeroic or nootropic, an agent that is specially designed to treat sleeping disorders by promoting wakefulness along with cognitive and mood enhancement, alertness, and in some patients a mild euphoria.
Scientists have discovered that dopamine acts within the pineal gland to help regulate circadian rhythms which in turn regulate sleep. Modalert also affects histamine levels within the brain which can help promote wakefulness during the day. While primarily used as a cognitive enhancing drug, Modalert has a secondary effect of appetite suppression which can aid in weight loss.
Modalert has a variety of uses and effects resulting in better energy levels, greater focus, improved sleep patterns and improved productivity. It has been known to significantly reduce drowsiness leading to greater cognitive function and being more alert and awake during the day.
Because of its ability to help with focus and concentration, students can benefit from using Modalert for studying. Modalert is also beneficial for improving short-term or working memory which can further aid study and enhance productivity.
In addition, its ability to suppress appetite also makes it helpful in assisting with weight loss. Keep in mind, however, that modafinil does not have the same thermogenic benefits as a stimulant like caffeine does, so it may not have the same powerful results.
The onset of an effectiveness of Modalert generally occurs within an hour after administration and the drug has a peak performance of six to eight hours depending upon dosage. It is highly recommended that individuals stagger their usage in cycles so that periods of non-usage can be employed to deter any tolerance that may develop.
Is it also recommended that the user not takes Modalert afternoon since the drug acts as a stimulant. Modalert has a long half-life meaning that it can stay in your system for up to 15 hours. So it is best to take the medication earlier in the day.
Because Modalert can be dehydrating, it is important to drink water throughout the day to avoid headaches. Like other stimulants, Modalert can act as a diuretic causing water to pass through an individual's system quicker. This makes it imperative to hydrate in order to replace the water you've lost.
Pregnant women and individuals with a history of irregular heartbeat, chest pain, heart attack, high blood pressure, stimulant or illegal drug abuse, kidney or liver disease, and mental illness should not take Modalert.
Every Modalert tablet contains high-grade modafinil and comes in a 100 mg or 200 mg dosage. The tablets come in super high-grade flexible aluminum blisters that contain ten tablets per strip for easy access, to help to protect the pills from damage, and to maintain freshness.
How to take Modalert most effectively depends upon the individual's usage pattern, weight and age. It is recommended for new users to start with 100mg until they can properly understand how their bodies will respond and tolerate the drug. Longer term users can take 200mg up to two times per day. The upper limit for the drug is 400mg per day although it is strongly suggested that an upper limit of 300mg per day be used instead.
Unlike other stimulants that can create stress on your cardiovascular system, Modalert does not alter or affect blood pressure or heart rate. There are some side effects associated with Modalert, though not all of them are unpleasant. Some users experience enhanced sensory perception with the sense of touch and vision being most affected. Colors and lights may appear brighter and some athletes have found that the drug enhances their hand-eye coordination.
Modafinil is generally viewed as safe, but each individual may respond differently to this medication. Some side effects include, but aren't limited to:
Some possible but rare side effects include:
Side effects can become more prevalent at higher doses. The following table lists a more comprehensive list of possibly adverse reactions found in clinical trials with their rate of occurrence as compared to a placebo:
Preferred Term | Modafinil (%) (n = 934) | Placebo (%) (n = 567) |
---|---|---|
Headache | 34 | 23 |
Nausea | 11 | 3 |
Nervousness | 7 | 3 |
Rhinitis | 7 | 6 |
Back Pain | 6 | 5 |
Diarrhea | 6 | 5 |
Anxiety | 5 | 1 |
Anxiety | 5 | 4 |
Dyspepsia | 5 | 4 |
Insomnia | 5 | 1 |
Anorexia | 4 | 1 |
Dry Mouth | 4 | 2 |
Pharyngitis | 4 | 2 |
Chest Pain | 3 | 1 |
Hypertension | 3 | 1 |
Abnormal Liver Function | 2 | 1 |
Constipation | 2 | 1 |
Depression | 2 | 1 |
Palpitation | 2 | 1 |
Paresthesia | 2 | 0 |
Somnolence | 2 | 1 |
Tachycardia | 2 | 1 |
Vasodilatation | 2 | 0 |
Abnormal Vision | 1 | 0 |
Agitation | 1 | 1 |
Asthma | 1 | 0 |
Chills | 1 | 0 |
Confusion | 1 | 0 |
Dyskenesia | 1 | 0 |
Edema | 1 | 0 |
Emotional Lability | 1 | 0 |
Eosinophilia | 1 | 0 |
Epistaxis | 1 | 0 |
Flatulence | 1 | 0 |
Hyperkinesia | 1 | 0 |
Hypertonia | 1 | 0 |
Mouth Ulceration | 1 | 0 |
Sweating | 1 | 0 |
Disturbances in taste | 1 | 0 |
Thirst | 1 | 0 |
Tremor | 1 | 0 |
Urine Abnormality | 1 | 0 |
Vertigo | 1 | 0 |
For those individuals concerned about whether or not Modalert will show up on a drug test, the answer is generally no. It can be detected in the blood and urine but a standard drug test does not usually screen for Modafinil.
It's important to consult your doctor before taking Modalert as the drug may interfere with other medications. Some known interactions include Monoamine Oxidase Inhibitors (MAO Inhibitors) and antidepressants including Marplan (isocarboxazid), Parnate (tranylcypromine), Nardil (phenelzine), Anafranil (clomipramine) and Norpramin (desipramine). Modalert should also not be taken with any nervous system stimulant such as ADHA treatments like Adderall, Ritalin, Concerta and Cylert to name a few.
The following drugs are also counteracted for modafinil: phenytoin (Dilantin); carbamazepine (Tegretol); phenobarbital; rifampin (Rifadin, Rimactane); ketoconazole (Nizoral); itraconazole (Sporanox); cyclosporine (Neoral, Sandimmune); theophylline (Theolair, Theochron, Theo-Bid, Theo-Dur, Elixophyllin, Slo-Phyllin, and others); warfarin (Coumadin); diazepam (Valium); or propranolol (Inderal).
This list is not comprehensive, so it is important to speak with your doctor before combining Modalert with another prescription drug.
Modafinil has received highly rated reviews from around the world. Users report positive experiences with the drug ranging from help with fatigue and sleep disorders (particularly shift work sleep disorder), increased concentration and focus, improved memory, increased an ability to brainstorm and "think outside of the box", and enhanced creativity. Users who wrote a review also reported preferring Modalert to other stimulants citing that other stimulants often caused jittery sensations and anxiety whereas Modalert did not.
I usually take Modalert to help with menial tasks in my office job, but I found that it actually help me focus when doing cardio (I ran for a couple of kilometers longer than normal). Delwin V.
Just thought I'd share a Modalert review since I've been taking these types of pill for over a year. Would definitely recommend Modalert over any other type as it works quicker (for me anyway). Syed S.
I had exams coming up and was feeling under pressure because I didn't have much time to study. This stuff really works - it enabled me to focus instead of procrastinating! Martin C.
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